Interactions of Aspirin and Hormonal Therapy in Men With Prostate Cancer
Carol L. Kornmehl, M.D., FACRO asked:
Copyright 2008 by Carol L. Kornmehl. All rights reserved. No part of this article may be reproduced without express written permission from the author.
Prostate cancer is a common diagnosis in men, especially in the older population. Other medical problems, such as heart disease, are also frequent in this age group.
Hormone therapy is a helpful treatment for many men with prostate cancer and aspirin is protective for those with heart disease. Since many of these men are diagnosed with both heart disease and prostate cancer, it seems intuitive that they should take both aspirin and hormone therapy.
Hormone therapy reduces the blood level of testosterone, the male hormone that prostate cancer cells tend to thrive on. Aspirin, on the other hand, is a blood thinner that helps to prevent blood clots and heart attacks. In addition, hormonal therapy can raise a man’s risk of having a heart attack, so taking baby aspirin seems like a sensible approach to decrease this possibility.
However, a recent study published in the New England Journal of Medicine evaluated the finding of elevated liver function blood tests in men using both agents. The study included 206 men with localized prostate cancer who were enrolled in a clinical trial to compare the outcome of radiation therapy alone versus radiation therapy plus six months of hormonal therapy.
Men who completed six months of hormonal therapy were three and a half times less likely to die from prostate cancer than men who received less than the full course. When liver function tests were found to be elevated, the implication was the hormone therapy had to be discontinued until the tests normalized.
As it turned out, men who took aspirin were more likely to need to discontinue hormone therapy. Extrapolating from animal data, investigators inferred that the amount of aspirin that entered the bloodstream was magnified 100-times in men who received hormone therapy.
Whenever treating a person, medical doctors need to weigh the benefits and risk of their medical decisions. Therefore, a compromise appears to be the following: men who take aspirin for prevention can forego it for the six months of hormonal therapy. On the other hand, a man who absolutely needs aspirin will forego hormone therapy instead.
The good news is that by practicing holistic medicine, such as by looking at the whole man and not just his medical problem(s), physicians can make the best decisions that affect the prolongation of the person’s life.
Fioricet blog, know more about fioricet
Copyright 2008 by Carol L. Kornmehl. All rights reserved. No part of this article may be reproduced without express written permission from the author.
Prostate cancer is a common diagnosis in men, especially in the older population. Other medical problems, such as heart disease, are also frequent in this age group.
Hormone therapy is a helpful treatment for many men with prostate cancer and aspirin is protective for those with heart disease. Since many of these men are diagnosed with both heart disease and prostate cancer, it seems intuitive that they should take both aspirin and hormone therapy.
Hormone therapy reduces the blood level of testosterone, the male hormone that prostate cancer cells tend to thrive on. Aspirin, on the other hand, is a blood thinner that helps to prevent blood clots and heart attacks. In addition, hormonal therapy can raise a man’s risk of having a heart attack, so taking baby aspirin seems like a sensible approach to decrease this possibility.
However, a recent study published in the New England Journal of Medicine evaluated the finding of elevated liver function blood tests in men using both agents. The study included 206 men with localized prostate cancer who were enrolled in a clinical trial to compare the outcome of radiation therapy alone versus radiation therapy plus six months of hormonal therapy.
Men who completed six months of hormonal therapy were three and a half times less likely to die from prostate cancer than men who received less than the full course. When liver function tests were found to be elevated, the implication was the hormone therapy had to be discontinued until the tests normalized.
As it turned out, men who took aspirin were more likely to need to discontinue hormone therapy. Extrapolating from animal data, investigators inferred that the amount of aspirin that entered the bloodstream was magnified 100-times in men who received hormone therapy.
Whenever treating a person, medical doctors need to weigh the benefits and risk of their medical decisions. Therefore, a compromise appears to be the following: men who take aspirin for prevention can forego it for the six months of hormonal therapy. On the other hand, a man who absolutely needs aspirin will forego hormone therapy instead.
The good news is that by practicing holistic medicine, such as by looking at the whole man and not just his medical problem(s), physicians can make the best decisions that affect the prolongation of the person’s life.
Fioricet blog, know more about fioricet
Tags: Hormone Therapy, Liver Function Blood Tests
The Joy of Living
Alex Hopkins asked:
It is an old saying that “Everything happens for our betterment” which means that we should accept whatever happens to us without making complaints as there is always something good in the things that happen. There are many people who accept everything that comes on their way happily, be it good or bad as they think it is for their betterment and the will from above. However, it makes me wonder if accident, death, sickness, robbery etc also happen for a person’s betterment as in these cases we seem to loose more than gain.
What if a healthy person suddenly suffers from serious illness? Will he be able to accept it and keep his condition unattended and say it’s the wish from above and has occurred for his own betterment or should he seek some medical treatment? Well, there are people I know, who in spite of having cold and fever endure and refuse to take medicine and wait to get healed naturally.
If your body suffers from serious injury and you are bed ridden for life, suffering pain all over, won’t you choose death than to undergo this painful ordeal? Well, many things happen in many cases for our own good and I think they happen so that we may experience harshness and come to appreciate health and learn the joy of living. Therefore, if we do not take medical treatment we will be punishing ourselves unnecessarily, so, we should take medical treatment and try to restore back our health.
Though we cannot prevent the sicknesses which befell us but we can stop the pain associated with the sickness and also halt the aggravation of our sickness. It is pain which makes sicknesses hard to endure and taking a medicine to relieve the pain speeds up the healing process. Remeber if the pain is not there we will not feel as sick as we actually are. Tramadol, approved by the FDA for treatment of acute to chronic pain, is one such pain relief pill which takes away your pain.
Tramadol is used in the treatment of moderate to severe pain of post-surgery and nerve disorder, it is also beneficial for the treatment of depression and anxiety. It is found to be the most effective treatment for relieving pain of the nerves such as postherpatic neuralgia and trigeminal neuralgia. It works by directly acting on the brain and the spine. It also suppresses the pain signal passing from one nerve to another nerve.
Tramadol comes in 50mg dosage and the dosage depends upon the kind of sickness and the severity of the pain felt and can be taken anytime which is appropriate for you with or without food. It is important to note that Tramadol is classified as opiate agonists and therefore can be abused, if you are planning to buy Tramadol for your medical treatment you will need to consult a physician.
Dizziness, weakness, nausea or vomiting, stomach upset, constipation, headache, drowsiness, anxiety, irritability, dry mouth or sweating are some of the mild side-effects of Tramadol which can be ignored and tolerated. However, if conditions like chest pain, rapid heart rate, skin rash or itching, mental confusion, disorientation, seizures, tingling of the hands or feet, trouble breathing occurs you must consult your doctor immediately and stop taking Tramadol.
Therefore, to see whether Tramadol is compatible with you it is a must to consult your doctor disclosing all your medical history. Once your doctor approves Tramadol for you, you can order Tramadol from a pharmacy of your choice.
TRamadol
It is an old saying that “Everything happens for our betterment” which means that we should accept whatever happens to us without making complaints as there is always something good in the things that happen. There are many people who accept everything that comes on their way happily, be it good or bad as they think it is for their betterment and the will from above. However, it makes me wonder if accident, death, sickness, robbery etc also happen for a person’s betterment as in these cases we seem to loose more than gain.
What if a healthy person suddenly suffers from serious illness? Will he be able to accept it and keep his condition unattended and say it’s the wish from above and has occurred for his own betterment or should he seek some medical treatment? Well, there are people I know, who in spite of having cold and fever endure and refuse to take medicine and wait to get healed naturally.
If your body suffers from serious injury and you are bed ridden for life, suffering pain all over, won’t you choose death than to undergo this painful ordeal? Well, many things happen in many cases for our own good and I think they happen so that we may experience harshness and come to appreciate health and learn the joy of living. Therefore, if we do not take medical treatment we will be punishing ourselves unnecessarily, so, we should take medical treatment and try to restore back our health.
Though we cannot prevent the sicknesses which befell us but we can stop the pain associated with the sickness and also halt the aggravation of our sickness. It is pain which makes sicknesses hard to endure and taking a medicine to relieve the pain speeds up the healing process. Remeber if the pain is not there we will not feel as sick as we actually are. Tramadol, approved by the FDA for treatment of acute to chronic pain, is one such pain relief pill which takes away your pain.
Tramadol is used in the treatment of moderate to severe pain of post-surgery and nerve disorder, it is also beneficial for the treatment of depression and anxiety. It is found to be the most effective treatment for relieving pain of the nerves such as postherpatic neuralgia and trigeminal neuralgia. It works by directly acting on the brain and the spine. It also suppresses the pain signal passing from one nerve to another nerve.
Tramadol comes in 50mg dosage and the dosage depends upon the kind of sickness and the severity of the pain felt and can be taken anytime which is appropriate for you with or without food. It is important to note that Tramadol is classified as opiate agonists and therefore can be abused, if you are planning to buy Tramadol for your medical treatment you will need to consult a physician.
Dizziness, weakness, nausea or vomiting, stomach upset, constipation, headache, drowsiness, anxiety, irritability, dry mouth or sweating are some of the mild side-effects of Tramadol which can be ignored and tolerated. However, if conditions like chest pain, rapid heart rate, skin rash or itching, mental confusion, disorientation, seizures, tingling of the hands or feet, trouble breathing occurs you must consult your doctor immediately and stop taking Tramadol.
Therefore, to see whether Tramadol is compatible with you it is a must to consult your doctor disclosing all your medical history. Once your doctor approves Tramadol for you, you can order Tramadol from a pharmacy of your choice.
TRamadol
Tags: Medical Treatment, Severe Pain
